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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name ESRG
ncRNA Category lncRNA
ID 790952
Ensembl ENSG00000265992
Synonyms HESRG
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line human induced pluripotent stem cells (hiPSCs), hiPSC-derived RPE cells (hiPSC-RPE)
Methods microarray, RT-PCR, qPCR, Fluorescent in situ hybridization, transfection, immunoblot, immunofluorescent staining
Expression pattern down-regulated
Functional description 13 lncRNAs showed a consistent fold change of over 2 among all time points along with the differentiation indicating their crucial roles in RPE differentiation.
PubMed ID 28880276
Year 2017
Title LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression.
Drug-related ncRNA NO

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